The purpose of this FOA is to support interdisciplinary community-engaged research designed to reduce or eliminate infections and sepsis as causes of pregnancy- related or associated morbidity and mortality (PRAMM) in regions of the United States with high rates of maternal mortality. This FOA is to support research primarily focused on PRAMM health disparities in areas with highest maternal morbidity and mortality.
This initiative utilizes the UG3/UH3 Phased Innovation Awards Cooperative Agreement and will be rolled out in 2 phases. Awards for the UG3 phase will be used to demonstrate sufficient preparation, feasibility, and capacity to meet foundational milestones specific to the work proposed. Hypothesis driven objectives will be submitted for the UH3 phase. A UG3 project that meets its milestones will be administratively considered by NICHD and prioritized for transition to the UH3 award. Applicants responding to this FOA must address objectives for both the UG3 and UH3 phases.