This Funding Opportunity Announcement (FOA), utilizing the U24 grant funding mechanism, invites applications for a Coordinating Center (CC) to establish a new population-based cohort study to address key population research gaps in the health of Asian Americans (AsA), Native Hawaiians, and Pacific Islanders (NHPI). This epidemiological cohort study will enable the enrollment, initial examination, and follow-up activities of a cohort of approximately 10,000 participants from multiple immigrant generations of ancestral Asian subpopulations, as well as Native Hawaiians and Pacific Islander subpopulations. Specifically, this initiative will utilize a “populomics” perspective, i.e., examination of health influences across multiple levels (biological, lifestyle/behavioral, environmental, sociocultural) using multi-disciplinary methods to investigate the web of influences impacting the health of AsA-NHPI subpopulations.
This U24 cooperative agreement is administered by the National Heart, Lung, and Blood Institute (NHLBI), but includes extensive participation and funding contributions from a coalition of institutes at the National Institutes of Health (NIH). This FOA aims to systematically investigate factors of risk and resilience and potential mediators impacting the health of AsA-NHPI subpopulations in parallel with a companion FOA (RFA-HL-23-015) that encourages applications for Clinical or Community Field Centers (CCFCs). Applications submitted to this FOA are expected to propose a detailed approach on how the applicant plans to serve as the Coordinating Center to achieve the necessary goals required for the entire duration of the award.