This Funding Opportunity Announcement (FOA) solicits Research Project Grant (R01) applications for projects designed to exploit variations (e.g., geographic, temporal) in social and health care policies to employ experimental, quasi-experimental, or other innovative approaches to uncover mechanisms driving disparities in care (i.e., access, utilization, and quality) for persons living with Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD).