NOT-AI-24-053 Notice of Special Interest (NOSI): Discovery and Development of Oral Small-molecule Direct-acting Antivirals Targeting Viruses of Pandemic Potential.

This Notice of Special Interest (NOSI) invites applications focused on the preclinical discovery, evaluation and development of oral direct-acting small molecule therapeutics targeting selected viruses of pandemic potential. The ultimate goal of this NOSI is to build a more robust pipeline of candidate antiviral drugs suitable for widespread use in the community in future outbreaks and/or pandemics.